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Completion of the entire hepatitis C virus life-cycle in genetically humanized mice

More than 130 million people world-wide chronically infected with hepatitis C virus (HCV) are at risk of developing severe liver disease. Antiviral treatments are only partially effective and a vaccine is not available. Development of more efficient therapies has been hampered by the lack of a small...

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Detalles Bibliográficos
Autores principales: Dorner, Marcus, Horwitz, Joshua A., Donovan, Bridget M., Labitt, Rachael N., Budell, William C., Friling, Tamar, Vogt, Alexander, Catanese, Maria Teresa, Satoh, Takashi, Kawai, Taro, Akira, Shizuo, Law, Mansun, Rice, Charles M., Ploss, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858853/
https://www.ncbi.nlm.nih.gov/pubmed/23903655
http://dx.doi.org/10.1038/nature12427