HS-173, a Novel PI3K Inhibitor, Attenuates the Activation of Hepatic Stellate Cells in Liver Fibrosis

Hepatic stellate cells (HSCs) are the primary source of matrix components in liver disease such as fibrosis. Phosphatidylinositol 3-kinase (PI3K) signaling in HSCs has been shown to induce fibrogenesis. In this study, we evaluated the anti-fibrotic activity of a novel imidazopyridine analogue (HS-17...

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Detalles Bibliográficos
Autores principales: Son, Mi Kwon, Ryu, Ye-Lim, Jung, Kyung Hee, Lee, Hyunseung, Lee, Hee Seung, Yan, Hong Hua, Park, Heon Joo, Ryu, Ji-Kan, Suh, Jun–Kyu, Hong, Sungwoo, Hong, Soon-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858860/
https://www.ncbi.nlm.nih.gov/pubmed/24326778
http://dx.doi.org/10.1038/srep03470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858860/
https://www.ncbi.nlm.nih.gov/pubmed/24326778
http://dx.doi.org/10.1038/srep03470

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