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An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice

Interleukin (IL)-33, the most recent member of the IL family of cytokines, signals through the ST2 receptor. IL-33/ST2 signaling mediates antigen challenge-induced mechanical hyperalgesia in the joints and cutaneous tissues of immunized mice. The present study asked whether IL-33/ST2 signaling is re...

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Detalles Bibliográficos
Autores principales: Magro, D.A.C., Hohmann, M.S.N., Mizokami, S.S., Cunha, T.M., Alves-Filho, J.C., Casagrande, R., Ferreira, S.H., Liew, F.Y., Cunha, F.Q., Verri, W.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859337/
https://www.ncbi.nlm.nih.gov/pubmed/23903682
http://dx.doi.org/10.1590/1414-431X20132894