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Attenuation of CCl(4)-Induced Hepatic Fibrosis in Mice by Vaccinating against TGF-β1

Transforming growth factor β1 (TGF-β1) is the pivotal pro-fibrogenic cytokine in hepatic fibrosis. Reducing the over-produced expression of TGF-β1 or blocking its signaling pathways is considered to be a promising therapeutic strategy for hepatic fibrosis. In this study, we evaluated the feasibility...

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Detalles Bibliográficos
Autores principales: Fan, Xiaobao, Zhang, Qiannan, Li, Shuang, Lv, Yifei, Su, Houqiang, Jiang, Huiping, Hao, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859579/
https://www.ncbi.nlm.nih.gov/pubmed/24349218
http://dx.doi.org/10.1371/journal.pone.0082190