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Attenuation of CCl(4)-Induced Hepatic Fibrosis in Mice by Vaccinating against TGF-β1
Transforming growth factor β1 (TGF-β1) is the pivotal pro-fibrogenic cytokine in hepatic fibrosis. Reducing the over-produced expression of TGF-β1 or blocking its signaling pathways is considered to be a promising therapeutic strategy for hepatic fibrosis. In this study, we evaluated the feasibility...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859579/ https://www.ncbi.nlm.nih.gov/pubmed/24349218 http://dx.doi.org/10.1371/journal.pone.0082190 |