New Therapeutic Approach: Diphenyl Diselenide Reduces Mitochondrial Dysfunction in Acetaminophen-Induced Acute Liver Failure

The acute liver failure (ALF) induced by acetaminophen (APAP) is closely related to oxidative damage and depletion of hepatic glutathione, consequently changes in cell energy metabolism and mitochondrial dysfunction have been observed after APAP overdose. Diphenyl diselenide [(PhSe)(2)], a simple or...

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Detalles Bibliográficos
Autores principales: Carvalho, Nélson R., da Rosa, Edovando F., da Silva, Michele H., Tassi, Cintia C., Dalla Corte, Cristiane L., Carbajo-Pescador, Sara, Mauriz, Jose L., González-Gallego, Javier, Soares, Félix A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859582/
https://www.ncbi.nlm.nih.gov/pubmed/24349162
http://dx.doi.org/10.1371/journal.pone.0081961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859582/
https://www.ncbi.nlm.nih.gov/pubmed/24349162
http://dx.doi.org/10.1371/journal.pone.0081961

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