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Quantitative Phosphoproteomic Analysis Identifies Activation of the RET and IGF-1R/IR Signaling Pathways in Neuroblastoma

Neuroblastoma is an embryonal tumor of childhood with a heterogenous clinical presentation that reflects differences in activation of complex biological signaling pathways. Protein phosphorylation is a key component of cellular signal transduction and plays a critical role in processes that control...

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Detalles Bibliográficos
Autores principales: DeNardo, Bradley D., Holloway, Michael P., Ji, Qinqin, Nguyen, Kevin T., Cheng, Yan, Valentine, Marcus B., Salomon, Arthur, Altura, Rachel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859635/
https://www.ncbi.nlm.nih.gov/pubmed/24349301
http://dx.doi.org/10.1371/journal.pone.0082513