The Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Displays Hippocampal Hyperexcitability, and Reduced Number of Interneurons, but No Presynaptic Vesicle Release Impairments

Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease. It is a fatal degenerative disease, best recognized for its debilitating neuromuscular effects. ALS however also induces cognitive impairments in as many as 50% of affected individuals. Moreover, many ALS patien...

Descripción completa

Detalles Bibliográficos
Autores principales: Thielsen, Karina D., Moser, Jakob M., Schmitt-John, Thomas, Jensen, Morten S., Jensen, Kimmo, Holm, Mai Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859636/
https://www.ncbi.nlm.nih.gov/pubmed/24349357
http://dx.doi.org/10.1371/journal.pone.0082767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859636/
https://www.ncbi.nlm.nih.gov/pubmed/24349357
http://dx.doi.org/10.1371/journal.pone.0082767

Ejemplares similares