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The Ciliary Protein Cystin Forms a Regulatory Complex with Necdin to Modulate Myc Expression
Cystin is a novel cilia-associated protein that is disrupted in the cpk mouse, a well-characterized mouse model of autosomal recessive polycystic kidney disease (ARPKD). Interestingly, overexpression of the Myc gene is evident in animal models of ARPKD and is thought to contribute to the renal cysti...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859662/ https://www.ncbi.nlm.nih.gov/pubmed/24349431 http://dx.doi.org/10.1371/journal.pone.0083062 |