An improved whole cell pertussis vaccine with reduced content of endotoxin

An improved whole cell pertussis vaccine, designated as Plow, which is low in endotoxicity due to a chemical extraction of lipo-oligosaccharide (LOS) from the outer membrane, was evaluated for safety, immunogenicity and potency, comparatively to a traditional whole cell pertussis vaccine. Current wh...

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Detalles Bibliográficos
Autores principales: Dias, Waldely Oliveira, van der Ark, Arno A.J., Sakauchi, Maria Aparecida, Kubrusly, Flávia Saldanha, Prestes, Ana Fabíola R.O., Borges, Monamaris Marques, Furuyama, Noemi, Horton, Denise S.P.Q., Quintilio, Wagner, Antoniazi, Marta, Kuipers, Betsy, van der Zeijst, Bernard A.M., Raw, Isaias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859757/
https://www.ncbi.nlm.nih.gov/pubmed/23291935
http://dx.doi.org/10.4161/hv.22847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859757/
https://www.ncbi.nlm.nih.gov/pubmed/23291935
http://dx.doi.org/10.4161/hv.22847

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