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Central cholinergic activation of a vagus nerve - to spleen circuit alleviates experimental colitis

The cholinergic anti-inflammatory pathway is an efferent vagus nerve-based mechanism that regulates immune responses and cytokine production through α7nicotinic-acetylcholinereceptor (α7nAChR) signaling. Decreased efferent vagus nerve activity is observed in inflammatory bowel disease (IBD). We dete...

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Detalles Bibliográficos
Autores principales: Ji, Hong, Rabbi, Mohammad F, Labis, Benoit, Pavlov, Valentin A, Tracey, Kevin J, Ghia, Jean-Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859808/
https://www.ncbi.nlm.nih.gov/pubmed/23881354
http://dx.doi.org/10.1038/mi.2013.52