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Central cholinergic activation of a vagus nerve - to spleen circuit alleviates experimental colitis
The cholinergic anti-inflammatory pathway is an efferent vagus nerve-based mechanism that regulates immune responses and cytokine production through α7nicotinic-acetylcholinereceptor (α7nAChR) signaling. Decreased efferent vagus nerve activity is observed in inflammatory bowel disease (IBD). We dete...
Autores principales: | Ji, Hong, Rabbi, Mohammad F, Labis, Benoit, Pavlov, Valentin A, Tracey, Kevin J, Ghia, Jean-Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859808/ https://www.ncbi.nlm.nih.gov/pubmed/23881354 http://dx.doi.org/10.1038/mi.2013.52 |
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