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The effects of tolvaptan on patients with severe chronic kidney disease complicated by congestive heart failure

BACKGROUND: Tolvaptan, a diuretic with a new mechanism of action, selectively binds to the vasopressin V2 receptor and inhibits reabsorption of water. Its effect on heart failure is proven, but its benefit for patients with chronic kidney disease (CKD) has not been not confirmed. In this study, we e...

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Detalles Bibliográficos
Autores principales: Otsuka, Tomoyuki, Sakai, Yukinao, Ohno, Dai, Murasawa, Tsuneo, Sato, Naoki, Tsuruoka, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859890/
https://www.ncbi.nlm.nih.gov/pubmed/23483323
http://dx.doi.org/10.1007/s10157-013-0788-6