Human fucosyltransferase 6 enables prostate cancer metastasis to bone

BACKGROUND: The interaction between human prostate cancer (PCa) cells and bone marrow (BM) endothelium follows a rolling-and-adhesion cascade mediated by E-selectin ligand (ESL): E-selectin. This adhesion is enabled by elevated expression of α-1,3-fucosyltransferases (FTs), enzymes responsible for E...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, J, Guillebon, A D, Hsu, J-w, Barthel, S R, Dimitroff, C J, Lee, Y-F, King, M R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859952/
https://www.ncbi.nlm.nih.gov/pubmed/24178760
http://dx.doi.org/10.1038/bjc.2013.690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859952/
https://www.ncbi.nlm.nih.gov/pubmed/24178760
http://dx.doi.org/10.1038/bjc.2013.690

Ejemplares similares