Therapeutic resistance in cancer: microRNA regulation of EGFR signaling networks

Receptor tyrosine kinases (RTKs) such as the epidermal growth factor receptor (EGFR) regulate cellular homeostatic processes. EGFR activates downstream signaling cascades that promote tumor cell survival, proliferation and migration. Dysregulation of EGFR signaling as a consequence of overexpression...

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Detalles Bibliográficos
Autores principales: Gomez, German G., Wykosky, Jill, Zanca, Ciro, Furnari, Frank B., Cavenee, Webster K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860350/
https://www.ncbi.nlm.nih.gov/pubmed/24349829
http://dx.doi.org/10.7497/j.issn.2095-3941.2013.04.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860350/
https://www.ncbi.nlm.nih.gov/pubmed/24349829
http://dx.doi.org/10.7497/j.issn.2095-3941.2013.04.003

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