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Ubiquitination-dependent quality control of hERG K(+) channel with acquired and inherited conformational defect at the plasma membrane
Membrane trafficking in concert with the peripheral quality control machinery plays a critical role in preserving plasma membrane (PM) protein homeostasis. Unfortunately, the peripheral quality control may also dispose of partially or transiently unfolded polypeptides and thereby contribute to the l...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861077/ https://www.ncbi.nlm.nih.gov/pubmed/24152733 http://dx.doi.org/10.1091/mbc.E13-07-0417 |