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Estrogen regulates histone deacetylases to prevent cardiac hypertrophy

The development and progression of cardiac hypertrophy often leads to heart failure and death, and important modulators of hypertrophy include the histone deacetylase proteins (HDACs). Estrogen inhibits cardiac hypertrophy and progression in animal models and humans. We therefore investigated the in...

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Detalles Bibliográficos
Autores principales: Pedram, Ali, Razandi, Mahnaz, Narayanan, Ramesh, Dalton, James T., McKinsey, Timothy A., Levin, Ellis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861078/
https://www.ncbi.nlm.nih.gov/pubmed/24152730
http://dx.doi.org/10.1091/mbc.E13-08-0444