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The Rac-GAP Bcr is a novel regulator of the Par complex that controls cell polarity

Cell polarization is essential for many biological processes, including directed cell migration, and loss of polarity contributes to pathological conditions such as cancer. The Par complex (Par3, Par6, and PKCζ) controls cell polarity in part by recruiting the Rac-specific guanine nucleotide exchang...

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Detalles Bibliográficos
Autores principales: Narayanan, Anjana S., Reyes, Steve B., Um, Kyongmi, McCarty, Joseph H., Tolias, Kimberley F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861082/
https://www.ncbi.nlm.nih.gov/pubmed/24152735
http://dx.doi.org/10.1091/mbc.E13-06-0333