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The Rac-GAP Bcr is a novel regulator of the Par complex that controls cell polarity
Cell polarization is essential for many biological processes, including directed cell migration, and loss of polarity contributes to pathological conditions such as cancer. The Par complex (Par3, Par6, and PKCζ) controls cell polarity in part by recruiting the Rac-specific guanine nucleotide exchang...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861082/ https://www.ncbi.nlm.nih.gov/pubmed/24152735 http://dx.doi.org/10.1091/mbc.E13-06-0333 |