The NuRD Chromatin-Remodeling Enzyme CHD4 Promotes Embryonic Vascular Integrity by Transcriptionally Regulating Extracellular Matrix Proteolysis

The extracellular matrix (ECM) supports vascular integrity during embryonic development. Proteolytic degradation of ECM components is required for angiogenesis, but excessive ECM proteolysis causes blood vessel fragility and hemorrhage. Little is understood about how ECM proteolysis is transcription...

Descripción completa

Detalles Bibliográficos
Autores principales: Ingram, Kyle G., Curtis, Carol D., Silasi-Mansat, Robert, Lupu, Florea, Griffin, Courtney T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861115/
https://www.ncbi.nlm.nih.gov/pubmed/24348274
http://dx.doi.org/10.1371/journal.pgen.1004031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861115/
https://www.ncbi.nlm.nih.gov/pubmed/24348274
http://dx.doi.org/10.1371/journal.pgen.1004031

Ejemplares similares