Cargando…

Alcohol-Induced Histone Acetylation Reveals a Gene Network Involved in Alcohol Tolerance

Sustained or repeated exposure to sedating drugs, such as alcohol, triggers homeostatic adaptations in the brain that lead to the development of drug tolerance and dependence. These adaptations involve long-term changes in the transcription of drug-responsive genes as well as an epigenetic restructu...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghezzi, Alfredo, Krishnan, Harish R., Lew, Linda, Prado, Francisco J., Ong, Darryl S., Atkinson, Nigel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861128/
https://www.ncbi.nlm.nih.gov/pubmed/24348266
http://dx.doi.org/10.1371/journal.pgen.1003986