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Alcohol-Induced Histone Acetylation Reveals a Gene Network Involved in Alcohol Tolerance
Sustained or repeated exposure to sedating drugs, such as alcohol, triggers homeostatic adaptations in the brain that lead to the development of drug tolerance and dependence. These adaptations involve long-term changes in the transcription of drug-responsive genes as well as an epigenetic restructu...
Autores principales: | Ghezzi, Alfredo, Krishnan, Harish R., Lew, Linda, Prado, Francisco J., Ong, Darryl S., Atkinson, Nigel S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861128/ https://www.ncbi.nlm.nih.gov/pubmed/24348266 http://dx.doi.org/10.1371/journal.pgen.1003986 |
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