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Genetic Recombination Is Targeted towards Gene Promoter Regions in Dogs

The identification of the H3K4 trimethylase, PRDM9, as the gene responsible for recombination hotspot localization has provided considerable insight into the mechanisms by which recombination is initiated in mammals. However, uniquely amongst mammals, canids appear to lack a functional version of PR...

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Detalles Bibliográficos
Autores principales: Auton, Adam, Rui Li, Ying, Kidd, Jeffrey, Oliveira, Kyle, Nadel, Julie, Holloway, J. Kim, Hayward, Jessica J., Cohen, Paula E., Greally, John M., Wang, Jun, Bustamante, Carlos D., Boyko, Adam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861134/
https://www.ncbi.nlm.nih.gov/pubmed/24348265
http://dx.doi.org/10.1371/journal.pgen.1003984