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Genetic Recombination Is Targeted towards Gene Promoter Regions in Dogs
The identification of the H3K4 trimethylase, PRDM9, as the gene responsible for recombination hotspot localization has provided considerable insight into the mechanisms by which recombination is initiated in mammals. However, uniquely amongst mammals, canids appear to lack a functional version of PR...
Autores principales: | Auton, Adam, Rui Li, Ying, Kidd, Jeffrey, Oliveira, Kyle, Nadel, Julie, Holloway, J. Kim, Hayward, Jessica J., Cohen, Paula E., Greally, John M., Wang, Jun, Bustamante, Carlos D., Boyko, Adam R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861134/ https://www.ncbi.nlm.nih.gov/pubmed/24348265 http://dx.doi.org/10.1371/journal.pgen.1003984 |
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