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TLR2 Ligands Induce NF-κB Activation from Endosomal Compartments of Human Monocytes

Localization of Toll-like receptors (TLR) in subcellular organelles is a major strategy to regulate innate immune responses. While TLR4, a cell-surface receptor, signals from both the plasma membrane and endosomal compartments, less is known about the functional role of endosomal trafficking upon TL...

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Detalles Bibliográficos
Autores principales: Brandt, Karim J., Fickentscher, Céline, Kruithof, Egbert. K. O., de Moerloose, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861177/
https://www.ncbi.nlm.nih.gov/pubmed/24349012
http://dx.doi.org/10.1371/journal.pone.0080743