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TLR2 Ligands Induce NF-κB Activation from Endosomal Compartments of Human Monocytes
Localization of Toll-like receptors (TLR) in subcellular organelles is a major strategy to regulate innate immune responses. While TLR4, a cell-surface receptor, signals from both the plasma membrane and endosomal compartments, less is known about the functional role of endosomal trafficking upon TL...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861177/ https://www.ncbi.nlm.nih.gov/pubmed/24349012 http://dx.doi.org/10.1371/journal.pone.0080743 |