Polyfunctional T Cell Responses in Children in Early Stages of Chronic Trypanosoma cruzi Infection Contrast with Monofunctional Responses of Long-term Infected Adults

BACKGROUND: Adults with chronic Trypanosoma cruzi exhibit a poorly functional T cell compartment, characterized by monofunctional (IFN-γ-only secreting) parasite-specific T cells and increased levels of terminally differentiated T cells. It is possible that persistent infection and/or sustained expo...

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Detalles Bibliográficos
Autores principales: Albareda, María C., De Rissio, Ana M., Tomas, Gonzalo, Serjan, Alicia, Alvarez, María G., Viotti, Rodolfo, Fichera, Laura E., Esteva, Mónica I., Potente, Daniel, Armenti, Alejandro, Tarleton, Rick L., Laucella, Susana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861186/
https://www.ncbi.nlm.nih.gov/pubmed/24349591
http://dx.doi.org/10.1371/journal.pntd.0002575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861186/
https://www.ncbi.nlm.nih.gov/pubmed/24349591
http://dx.doi.org/10.1371/journal.pntd.0002575

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