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Changes in Mitochondrial Carriers Exhibit Stress-Specific Signatures in INS-1Eβ-Cells Exposed to Glucose Versus Fatty Acids

Chronic exposure of β-cells to metabolic stresses impairs their function and potentially induces apoptosis. Mitochondria play a central role in coupling glucose metabolism to insulin secretion. However, little is known on mitochondrial responses to specific stresses; i.e. low versus high glucose, sa...

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Detalles Bibliográficos
Autores principales: Brun, Thierry, Scarcia, Pasquale, Li, Ning, Gaudet, Pascale, Duhamel, Dominique, Palmieri, Ferdinando, Maechler, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861392/
https://www.ncbi.nlm.nih.gov/pubmed/24349266
http://dx.doi.org/10.1371/journal.pone.0082364