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Design, Synthesis of Novel Lipids as Chemical Permeation Enhancers and Development of Nanoparticle System for Transdermal Drug Delivery

In the present study, we designed and developed novel lipids that include (Z)-1-(Octadec-9-en-1-yl)-pyrrolidine (Cy5T), 1, 1-Di-((Z)-octadec-9-en-1-yl)pyrrolidin-1-ium iodide (Cy5), (Z)-1-(Octadec-9-en-1-yl)-piperidine (Cy6T), and 1, 1-Di-((Z)-octadec-9-en-1-yl) piperidin-1-ium iodide (Cy6) to enhan...

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Detalles Bibliográficos
Autores principales: Marepally, Srujan, Boakye, Cedar H. A., Shah, Punit P., Etukala, Jagan Reddy, Vemuri, Adithi, Singh, Mandip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861410/
https://www.ncbi.nlm.nih.gov/pubmed/24349315
http://dx.doi.org/10.1371/journal.pone.0082581