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Human L-ficolin, a Recognition Molecule of the Lectin Activation Pathway of Complement, Activates Complement by Binding to Pneumolysin, the Major Toxin of Streptococcus pneumoniae

The complement system is an essential component of the immune response, providing a critical line of defense against different pathogens including S. pneumoniae. Complement is activated via three distinct pathways: the classical (CP), the alternative (AP) and the lectin pathway (LP). The role of Pne...

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Detalles Bibliográficos
Autores principales: Ali, Youssif M., Kenawy, Hany I., Muhammad, Adnan, Sim, Robert B., Andrew, Peter W., Schwaeble, Wilhelm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861440/
https://www.ncbi.nlm.nih.gov/pubmed/24349316
http://dx.doi.org/10.1371/journal.pone.0082583