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Human L-ficolin, a Recognition Molecule of the Lectin Activation Pathway of Complement, Activates Complement by Binding to Pneumolysin, the Major Toxin of Streptococcus pneumoniae
The complement system is an essential component of the immune response, providing a critical line of defense against different pathogens including S. pneumoniae. Complement is activated via three distinct pathways: the classical (CP), the alternative (AP) and the lectin pathway (LP). The role of Pne...
Autores principales: | Ali, Youssif M., Kenawy, Hany I., Muhammad, Adnan, Sim, Robert B., Andrew, Peter W., Schwaeble, Wilhelm J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861440/ https://www.ncbi.nlm.nih.gov/pubmed/24349316 http://dx.doi.org/10.1371/journal.pone.0082583 |
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