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Time Scales in Epigenetic Dynamics and Phenotypic Heterogeneity of Embryonic Stem Cells
A remarkable feature of the self-renewing population of embryonic stem cells (ESCs) is their phenotypic heterogeneity: Nanog and other marker proteins of ESCs show large cell-to-cell variation in their expression level, which should significantly influence the differentiation process of individual c...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861442/ https://www.ncbi.nlm.nih.gov/pubmed/24348228 http://dx.doi.org/10.1371/journal.pcbi.1003380 |