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Recombinant IL-7/HGFβ Hybrid Cytokine Enhances T Cell Recovery in Mice Following Allogeneic Bone Marrow Transplantation

T cell immunodeficiency is a major complication of bone marrow (BM) transplantation (BMT). Therefore, approaches to enhance T cell reconstitution after BMT are required. We have purified a hybrid cytokine, consisting of IL-7 and the β-chain of hepatocyte growth factor (HGFβ) (IL-7/HGFβ), from a uniq...

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Detalles Bibliográficos
Autores principales: Lai, Laijun, Zhang, Mingfeng, Song, Yinhong, Rood, Debra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861470/
https://www.ncbi.nlm.nih.gov/pubmed/24349415
http://dx.doi.org/10.1371/journal.pone.0082998