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Pyrrolidine dithiocarbamate (PDTC) inhibits the overexpression of MCP-1 and attenuates microglial activation in the hippocampus of a pilocarpine-induced status epilepticus rat model

The aim of this study was to investigate the effects of pyrrolidine dithiocarbamate (PDTC) on MCP-1 expression and microglial activation in the hippocampus of a rat model of pilocarpine (PILO)-induced status epilepticus (SE). Moreover, seizure susceptibility, frequency and severity as well as brain...

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Detalles Bibliográficos
Autores principales: LV, RILANG, XU, XIAOYUN, LUO, ZHENG, SHEN, NAN, WANG, FENG, ZHAO, YONGBO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861516/
https://www.ncbi.nlm.nih.gov/pubmed/24348761
http://dx.doi.org/10.3892/etm.2013.1397