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Glycolytic ATP Fuels the Plasma Membrane Calcium Pump Critical for Pancreatic Cancer Cell Survival

Pancreatic cancer is an aggressive cancer with poor prognosis and limited treatment options. Cancer cells rapidly proliferate and are resistant to cell death due, in part, to a shift from mitochondrial metabolism to glycolysis. We hypothesized that this shift is important in regulating cytosolic Ca(...

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Detalles Bibliográficos
Autores principales: James, Andrew D., Chan, Anthony, Erice, Oihane, Siriwardena, Ajith K., Bruce, Jason I. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861649/
https://www.ncbi.nlm.nih.gov/pubmed/24158437
http://dx.doi.org/10.1074/jbc.M113.502948