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Glycolytic ATP Fuels the Plasma Membrane Calcium Pump Critical for Pancreatic Cancer Cell Survival
Pancreatic cancer is an aggressive cancer with poor prognosis and limited treatment options. Cancer cells rapidly proliferate and are resistant to cell death due, in part, to a shift from mitochondrial metabolism to glycolysis. We hypothesized that this shift is important in regulating cytosolic Ca(...
Autores principales: | James, Andrew D., Chan, Anthony, Erice, Oihane, Siriwardena, Ajith K., Bruce, Jason I. E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861649/ https://www.ncbi.nlm.nih.gov/pubmed/24158437 http://dx.doi.org/10.1074/jbc.M113.502948 |
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