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MAPK Hog1 closes the S. cerevisiae glycerol channel Fps1 by phosphorylating and displacing its positive regulators

The aquaglyceroprin Fps1 is responsible for glycerol transport in yeast in response to changes in extracellular osmolarity. Control of Fps1 channel activity in response to hyperosmotic shock involves a redundant pair of regulators, Rgc1 (regulator of the glycerol channel 1) and Rgc2, and the MAPK Ho...

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Detalles Bibliográficos
Autores principales: Lee, Jongmin, Reiter, Wolfgang, Dohnal, Ilse, Gregori, Christa, Beese-Sims, Sara, Kuchler, Karl, Ammerer, Gustav, Levin, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861672/
https://www.ncbi.nlm.nih.gov/pubmed/24298058
http://dx.doi.org/10.1101/gad.229310.113