Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours

Massively parallel sequencing offers the ability to interrogate a tumour biopsy for multiple mutational changes. For clinical samples, methodologies must enable maximal extraction of available sequence information from formalin-fixed and paraffin-embedded (FFPE) material. We assessed the use of targ...

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Detalles Bibliográficos
Autores principales: Wong, Stephen Q., Li, Jason, Salemi, Renato, Sheppard, Karen E., Hongdo Do, Tothill, Richard W., McArthur, Grant A., Dobrovic, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861801/
https://www.ncbi.nlm.nih.gov/pubmed/24336498
http://dx.doi.org/10.1038/srep03494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861801/
https://www.ncbi.nlm.nih.gov/pubmed/24336498
http://dx.doi.org/10.1038/srep03494

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