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Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours
Massively parallel sequencing offers the ability to interrogate a tumour biopsy for multiple mutational changes. For clinical samples, methodologies must enable maximal extraction of available sequence information from formalin-fixed and paraffin-embedded (FFPE) material. We assessed the use of targ...
Autores principales: | Wong, Stephen Q., Li, Jason, Salemi, Renato, Sheppard, Karen E., Hongdo Do, Tothill, Richard W., McArthur, Grant A., Dobrovic, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861801/ https://www.ncbi.nlm.nih.gov/pubmed/24336498 http://dx.doi.org/10.1038/srep03494 |
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