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Lipid- and sugar-modified endomorphins: novel targets for the treatment of neuropathic pain

Endomorphins are endogenous opioid peptides that cause potent antinociception in rodent models of acute and neuropathic pain with less undesirable side effects than opioid alkaloids. However, endomorphins are poorly suited to clinical applications because of low membrane permeability and a susceptib...

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Detalles Bibliográficos
Autores principales: Varamini, Pegah, Toth, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862115/
https://www.ncbi.nlm.nih.gov/pubmed/24379782
http://dx.doi.org/10.3389/fphar.2013.00155