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Lipid- and sugar-modified endomorphins: novel targets for the treatment of neuropathic pain
Endomorphins are endogenous opioid peptides that cause potent antinociception in rodent models of acute and neuropathic pain with less undesirable side effects than opioid alkaloids. However, endomorphins are poorly suited to clinical applications because of low membrane permeability and a susceptib...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862115/ https://www.ncbi.nlm.nih.gov/pubmed/24379782 http://dx.doi.org/10.3389/fphar.2013.00155 |