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A conditional predictive p-value to compare a multinomial with an overdispersed multinomial in the analysis of T-cell populations

Immunological experiments that record primary molecular sequences of T-cell receptors produce moderate to high-dimensional categorical data, some of which may be subject to extra-multinomial variation caused by technical constraints of cell-based assays. Motivated by such experiments in melanoma res...

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Detalles Bibliográficos
Autores principales: Pei, Qinglin, Zuleger, Cindy L., Macklin, Michael D., Albertini, Mark R., Newton, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862212/
https://www.ncbi.nlm.nih.gov/pubmed/24096387
http://dx.doi.org/10.1093/biostatistics/kxt039