Molecular characterization of the MRPA transporter and antimony uptake in four New World Leishmania spp. susceptible and resistant to antimony()

ATP-binding cassette (ABC) transporters have been associated with drug resistance in various diseases. The MRPA gene, a transporter of ABCC subfamily, is involved in the resistance by sequestering metal-thiol conjugates in intracellular vesicles of Leishmania parasite. In this study, we performed th...

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Detalles Bibliográficos
Autores principales: Moreira, Douglas S., Monte Neto, Rubens L., Andrade, Juvana M., Santi, Ana Maria M., Reis, Priscila G., Frézard, Frédéric, Murta, Silvane M.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862441/
https://www.ncbi.nlm.nih.gov/pubmed/24533304
http://dx.doi.org/10.1016/j.ijpddr.2013.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862441/
https://www.ncbi.nlm.nih.gov/pubmed/24533304
http://dx.doi.org/10.1016/j.ijpddr.2013.08.001

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