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Identification of mutations in TgMAPK1 of Toxoplasma gondii conferring resistance to 1NM-PP1()

Toxoplasma gondii is an important food and waterborne pathogen that causes severe disease in immunocompromised patients. Bumped kinase inhibitors (BKIs) have an antiparasitic effect on T. gondii tachyzoite growth by targeting T. gondii calmodulin-domain protein kinase 1 (TgCDPK1). To identify mutati...

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Detalles Bibliográficos
Autores principales: Sugi, Tatsuki, Kobayashi, Kyousuke, Takemae, Hitoshi, Gong, Haiyan, Ishiwa, Akiko, Murakoshi, Fumi, Recuenco, Frances C., Iwanaga, Tatsuya, Horimoto, Taisuke, Akashi, Hiroomi, Kato, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862444/
https://www.ncbi.nlm.nih.gov/pubmed/24533298
http://dx.doi.org/10.1016/j.ijpddr.2013.04.001