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Identification of mutations in TgMAPK1 of Toxoplasma gondii conferring resistance to 1NM-PP1()
Toxoplasma gondii is an important food and waterborne pathogen that causes severe disease in immunocompromised patients. Bumped kinase inhibitors (BKIs) have an antiparasitic effect on T. gondii tachyzoite growth by targeting T. gondii calmodulin-domain protein kinase 1 (TgCDPK1). To identify mutati...
Autores principales: | Sugi, Tatsuki, Kobayashi, Kyousuke, Takemae, Hitoshi, Gong, Haiyan, Ishiwa, Akiko, Murakoshi, Fumi, Recuenco, Frances C., Iwanaga, Tatsuya, Horimoto, Taisuke, Akashi, Hiroomi, Kato, Kentaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862444/ https://www.ncbi.nlm.nih.gov/pubmed/24533298 http://dx.doi.org/10.1016/j.ijpddr.2013.04.001 |
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