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Immunization of Chlamydia pneumoniae (Cpn)-Infected Apob(tm2Sgy)Ldlr(tm1Her)/J Mice with a Combined Peptide of Cpn Significantly Reduces Atherosclerotic Lesion Development

OBJECTIVE: To investigate the antigenic effect of a peptide containing two epitopes of Chlamydia pneumoniae (Cpn) on atherosclerotic lesion formation in mice infected with Cpn. MATERIALS AND METHODS: Six-week-old Apob(tm2Sgy)Ldlr(tm1Her)/J mice were immunized using a repetitive immunization multiple...

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Detalles Bibliográficos
Autores principales: Xia, Min, Chen, Daxin, Endresz, Valeria, Faludi, Ildiko, Szabo, Andrea, Gonczol, Eva, Kakkar, Vijay, Lu, Xinjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862476/
https://www.ncbi.nlm.nih.gov/pubmed/24349031
http://dx.doi.org/10.1371/journal.pone.0081056