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Survivin-3B promotes chemoresistance and immune escape by inhibiting caspase-8 and -6 in cancer cells
Survivin-3B (S-3B), an alternative splice isoform of survivin, plays a key role in tumorigenesis. S-3B promotes the escape of malignant cells from immune recognition by blocking the cytotoxicity of natural killer (NK) cells. Such an effect reflects the ability of S-3B to interfere with the assembly...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862639/ https://www.ncbi.nlm.nih.gov/pubmed/24353917 http://dx.doi.org/10.4161/onci.26328 |