Erythrina mulungu Alkaloids Are Potent Inhibitors of Neuronal Nicotinic Receptor Currents in Mammalian Cells

Crude extracts and three isolated alkaloids from Erythrina mulungu plants have shown anxiolytic effects in different animal models. We investigated whether these alkaloids could affect nicotinic acetylcholine receptors and if they are selective for different central nervous system (CNS) subtypes. Sc...

Descripción completa

Detalles Bibliográficos
Autores principales: Setti-Perdigão, Pedro, Serrano, Maria A. R., Flausino, Otávio A., Bolzani, Vanderlan S., Guimarães, Marília Z. P., Castro, Newton G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862643/
https://www.ncbi.nlm.nih.gov/pubmed/24349349
http://dx.doi.org/10.1371/journal.pone.0082726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862643/
https://www.ncbi.nlm.nih.gov/pubmed/24349349
http://dx.doi.org/10.1371/journal.pone.0082726

Ejemplares similares