Hemodialysis does not alter in vitro hepatic CYP3A4 and CYP2D6 metabolic activity in uremic serum

There is a paucity of studies evaluating the change in liver metabolism in subjects receiving hemodialysis. The purpose of this study was to compare the effect of uremic toxins on hepatic cytochrome P450 (CYP)3A4 and CYP2D6 metabolism before and after a 4-hour hemodialysis session. Midazolam and dex...

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Detalles Bibliográficos
Autores principales: Decker, Brian S, O’Neill, Kalisha D, Chambers, Mary A, Slaven, James E, Yu, Zhangsheng, Jones, David R, Moe, Sharon M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862653/
https://www.ncbi.nlm.nih.gov/pubmed/24353447
http://dx.doi.org/10.2147/CPAA.S54381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862653/
https://www.ncbi.nlm.nih.gov/pubmed/24353447
http://dx.doi.org/10.2147/CPAA.S54381

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