ADP Protects Cardiac Mitochondria under Severe Oxidative Stress

ADP is not only a key substrate for ATP generation, but also a potent inhibitor of mitochondrial permeability transition pore (mPTP). In this study, we assessed how oxidative stress affects the potency of ADP as an mPTP inhibitor and whether its reduction of reactive oxygen species (ROS) production...

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Detalles Bibliográficos
Autores principales: Sokolova, Niina, Pan, Shi, Provazza, Sarah, Beutner, Gisela, Vendelin, Marko, Birkedal, Rikke, Sheu, Shey-Shing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862761/
https://www.ncbi.nlm.nih.gov/pubmed/24349464
http://dx.doi.org/10.1371/journal.pone.0083214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862761/
https://www.ncbi.nlm.nih.gov/pubmed/24349464
http://dx.doi.org/10.1371/journal.pone.0083214

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