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Double-Strand Break Repair by Interchromosomal Recombination: An In Vivo Repair Mechanism Utilized by Multiple Somatic Tissues in Mammals

Homologous recombination (HR) is essential for accurate genome duplication and maintenance of genome stability. In eukaryotes, chromosomal double strand breaks (DSBs) are central to HR during specialized developmental programs of meiosis and antigen receptor gene rearrangements, and form at unusual...

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Detalles Bibliográficos
Autores principales: White, Ryan R., Sung, Patricia, Vestal, C. Greer, Benedetto, Gregory, Cornelio, Noelle, Richardson, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862804/
https://www.ncbi.nlm.nih.gov/pubmed/24349572
http://dx.doi.org/10.1371/journal.pone.0084379