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Clinical features of MS associated with Leber hereditary optic neuropathy mtDNA mutations

OBJECTIVE: To determine whether the association between multiple sclerosis (MS) and Leber hereditary optic neuropathy (LHON) (known as “Harding disease”) is a chance finding, or the 2 disorders are mechanistically linked. METHODS: We performed a United Kingdom–wide prospective cohort study of preval...

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Detalles Bibliográficos
Autores principales: Pfeffer, Gerald, Burke, Ailbhe, Yu-Wai-Man, Patrick, Compston, D. Alastair S., Chinnery, Patrick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863351/
https://www.ncbi.nlm.nih.gov/pubmed/24198293
http://dx.doi.org/10.1212/01.wnl.0000437308.22603.43