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Characterization of the male Apc(Min/+) mouse as a hypogonadism model related to cancer cachexia

Cancer cachexia, the unintentional loss of lean body mass, is associated with decreased quality of life and poor patient survival. Hypogonadism, involving a reduction in circulating testosterone, is associated with the cachectic condition. At this time there is a very limited understanding of the ro...

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Detalles Bibliográficos
Autores principales: White, James P., Puppa, Melissa J., Narsale, Aditi, Carson, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863419/
https://www.ncbi.nlm.nih.gov/pubmed/24285707
http://dx.doi.org/10.1242/bio.20136544